History Of T - Virus
History
t-Virus Project
On September 19, 1977 after conducting countless experiments within the laboratory adjacent to the Umbrella Research Center in the Arklay Mountains, Marcus had discovered a method of creating a new, more powerful virus using the Progenitor virus as the base element and mixing it with leech DNA. After the virus was administered to a leech, it underwent transformations and became violent and aggressive. Upon examining the blood of the leech, the basis for the t-virus was discovered. Marcus continued development and the virus was completed on January 13, 1978. Shortly after, Marcus conducted experiments on several animal species including monkeys, insects and frogs (eventually leading to the development of the Eliminator, Lurker and Plague Crawler) mimicking experiments previously carried out using the Progenitor virus. While definite results were observed, Marcus ended the experiments furiously after not getting the results he desired, ending with the belief that humans were the only viable test subjects.Soon after the creation of the t-virus, one of the executive candidates who he had fiercely trusted known as Albert Wesker revealed information to Ozwell E. Spencer, another founder of Umbrella who Marcus had recently come into bitter terms with, about Marcus' research. Spencer ordered several Umbrella employees to retrieve a sample of the virus from Marcus. However, they were unsuccessful, instead becoming specimens for Marcus' research. In the time that followed, many unwilling human test subjects were victims of Marcus' experiments - including several junior executive candidates at the Research Center, with the total victim count being around 20. The t-virus was later stolen from Marcus by Wesker and William Birkin, another student at the Research Center who Marcus trusted. Afterwards, Spencer closed the Research Center and moved all t-virus research to the nearby Arklay Laboratory. Here, the t-Virus Project began in earnest.
First Phase
At the top-secret Arklay Laboratory, Wesker and Birkin became chief researchers in charge of R&D into the t-virus and B.O.W. research. What became known as the "First Phase" of t-virus development following its initial completion was an effort to stabilise the virus well enough to produce viable Bio Organic Weapons. In total, it took 3 years for such a result to be realized. During early experiments with the virus, spiders were accidentally infected with it. Umbrella researchers in the Arklay Laboratory took note of this and began conducting injection tests on large, poisonous spiders to test their potential application as B.O.W. The result of this project was the "Web Spinner".Second Phase
In 1981, after several experiments on humans were conducted, the virus finally became stable enough to produce a living biological weapon in the form of the "Zombie" creature and the project reached its Second Phase with the ability to be used directly for genetic manipulation.Due to compatibility issues between the virus and the human genome, it became clear that the virus would only infect 90% of a population with the remaining 10% being unaffected as a result of natural immunity. Unhappy with this development, Spencer ordered for a 100% infection rate. Meanwhile, Birkin engineered a biological weapon with an increased emphasis on fighting ability by combining the genetic material of another creature with a fertilized human egg and administering the t-virus, producing a creature capable of killing all human beings in a designated target zone. The virus caused the embryos to grow much more quickly than normal and this B.O.W. was later officially dubbed "Hunter".
In 1983, Wesker began to ponder about the adaptability of the t-virus and the risk of secondary infection, due to it being able to infect and mutate the genomes of both animal and plants alike. Among the research conducted during the Second Phase, other B.O.W. were produced from other creatures. These included the earlier spider-based "Web Spinner", the "Cerberus", based on military trained Dobermans and "Neptune", based on a Great White shark. The final result of the facility's experiments was the "Chimera", developed like the Hunter by mutating the human genome with the t-virus and combining the genetic material of a fly. A rumoured 5th B.O.W. was also produced, known as the "Tick", an insect-based subspecies related to the Hunter and Chimera.
By 1988, as the project was about to enter its Third Phase, certain figures within Umbrella called for the research of James Marcus to be shut down. Under top-secret orders from Spencer himself and in exchange for his money, Wesker and Birkin assassinated Marcus and stole all of his research for use in their own project. As a research team conducted an investigation on the B.O.W. produced by Marcus, they, like Marcus, deduced that humans were the most viable test subjects for the virus. In response, the Arklay B.O.W. Research Team commenced the Tyrant Project under Birkin's direction.
Third Phase
The Third Phase of the t-virus project began in full with the Tyrant Project-- the goal to produce the ultimate B.O.W. The B.O.W. in question was a highly sophisticated fighting biological weapon, a super-soldier capable of receiving and understanding orders and carrying them out with utmost efficiency-- dubbed "Tyrant" after the project and the virus itself. Unlike previous experiments, the Tyrant would not be an animal, but a human subject. The idea was to administer the t-virus to a human subject and adapt it fully to the host. However, a huge problem lay with the fact that the strain of the t-virus used to create Zombies and Hunters was deemed unsuitable due to its tendency to destroy the subject's brain cells, limiting intelligence, which was required to successfully develop a Tyrant. In order to correct this issue, Birkin worked to extract and develop a t-virus variant which would cause the least amount of damage to the brain, preserving as much intelligence as possible. However, the Genetic Analytic team at the Arklay Laboratory turned up another issue, only 1 in 10 million people would possess a genetic compatibility to the new variant, the remainder would merely become Zombies.With the project at a standstill, Wesker instead set his sights on the parasite developed by the Sixth Laboratory in France. After administering the parasite to Lisa Trevor, they observed changes which would later become the genesis of the G-virus and in response, Wesker left the Arklay B.O.W. Research Team in 1991 to become an Umbrella intelligence agent. Not long after in December 1991, one Sergei Vladimir approached Umbrella. After passing the test for becoming a Tyrant, Sergei was convinced by Nicholai Zinoviev to turn over 10 clones of himself to Umbrella. Sergei did so in the end, and the Tyrant Project and the t-Virus Project in general resumed.
With compatible specimens at the ready, the Arklay Laboratory initially produced two Tyrants-- the failed Proto Tyrant (T-001 Type) and the successful Tyrant (T-002 Type), which was formally named after the virus and considered the ultimate bioweapon. T-001 was a success in theory; it presented all of the characteristics of a successful B.O.W. However the lack of further development into controlling the mutative and erosive nature of the t-virus meant that it was far from perfect. The T-002 was aimed at rectifying this issue. The T-002, unlike the T-001, was kept in development for a longer time to make further refinements and improvements, and was nurtured so as to reach its full potential. The T-002 was a vast improvement over the T-001; stronger, faster, more agile and able to be controlled and follow simple orders. Meanwhile, another Tyrant model was developed elsewhere. This model, the "Tyrant T-103 Type" was superior to the previous two, but required the data of the T-002 to be completed. After a successful experiment with the T-002, the Arklay B.O.W. Research Team also commenced the "Talos Project"-- producing the T-A.L.O.S. prototype.
Some sections of Umbrella began to engineer the virus for use in "virus therapy" as a treatment for cancer and normally fatal, cancerous illnesses. One of these strains was bought by Javier Hidalgo as a drug to treat his wife's fatal illness. In 1993, another strain of this nature known as T-JCCC203 was delivered to the private hospital in Raccoon Forest for experimentation, applied to patients (or rather, test subjects) Doug Frost and Dorothy Lester. These strains appear to wipe out the cancerous elements at first, but the virus still turns the subject into a monster by the end. Hilda became a large amphibious creature due to her repeated injections of the virus, whilst Dorothy Lester became a Zombie.
Further Developments
Over the years, t-virus R&D was continued by Umbrella and its branch facilities all over the globe who began to use the new discoveries in their own research to improve on the developments begun at Arklay. The Sixth Laboratory of the France branch directly administered by Umbrella Headquarters had mobilized the Nemesis Project to its full potential following the Mansion Incident with the creation of the Nemesis-T Type. The B.O.W. development team and genetic engineering research department on Sheena Island developed a method of artificial selection of superior genes through a cellular 'battle'. These superior genes would then be administered during the Tyrant cultivation process-- resulting in the Hypnos-T Type.Umbrella refused to abort research on the virus and continued selling it as a viral weapon.
Post-Umbrella
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